Structural and Functional Analysis of Bacillus subtilis YisP Reveal a Role of its Product in Biofilm Production

YisP is involved in biofilm formation in Bacillus subtilis and has been predicted to produce C30 isoprenoids. We determined the structure of YisP and observe that it adopts the same fold as squalene and dehydrosqualene synthases. However, the first aspartate-rich motif found in essentially all isopr...

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Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Feng, Xinxin, Hu, Yumei, Zheng, Yingying, Zhu, Wei, Li, Kai, Huang, Chun-Hsiang, Ko, Tzu-Ping, Ren, Feifei, Chan, Hsiu-Chien, Nega, Mulugeta, Bogue, Shannon, López, Daniel, Kolter, Roberto, Götz, Friedrich, Guo, Rey-Ting, Oldfield, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252625/
https://ncbi.nlm.nih.gov/pubmed/25308276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.08.018
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