Bacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase

We synthesized a series of benzoic acids and phenylphosphonic acids and investigated their effects on the growth of Staphylococcus aureus and Bacillus subtilis. One of the most active compounds (7, 5-fluoro-2-(3-(octyloxy)benzamido)benzoic acid, ED(50) ~ 0.15 μg/mL) acted synergistically with seven...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Wang, Yang, Desai, Janish, Zhang, Yonghui, Malwal, Satish R., Shin, Christopher J., Feng, Xinxin, Sun, Hong, Liu, Guizhi, Guo, Rey-Ting, Oldfield, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155509/
https://ncbi.nlm.nih.gov/pubmed/27578312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600342
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