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Structure, Function and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase
We report the first structure of heptaprenyl diphosphate synthase from Staphylococcus aureus (SaHepPPS), together with an investigation of its mechanism of action, and inhibition. The protein is involved in the formation of menaquinone, a key electron transporter in many bacteria, including pathogen...
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| Publicado no: | ChemMedChem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012948/ https://ncbi.nlm.nih.gov/pubmed/27457559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600311 |
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