Structure and Function of a “Head-to-Middle” Prenyltransferase: Lavandulyl Diphosphate Synthase

We report the first X-ray structure of the unique “head-to-middle” monoterpene synthase, lavandulyl diphosphate synthase (LPPS). LPPS catalyzes the condensation of two molecules of dimethylallyl diphosphate (DMAPP) to form lavandulyl diphosphate, a precursor to the fragrance lavandulol. The structur...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Liu, Meixia, Chen, Chun-Chi, Chen, Lu, Xiao, Xiansha, Zheng, Yingying, Huang, Jian-Wen, Liu, Weidong, Ko, Tzu-Ping, Cheng, Ya-Shan, Feng, Xinxin, Oldfield, Eric, Guo, Rey-Ting, Ma, Yanhe
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782148/
https://ncbi.nlm.nih.gov/pubmed/26922900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201600656
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