Characterization of Potential Drug Targets Farnesyl Diphosphate Synthase and Geranylgeranyl Diphosphate Synthase in Schistosoma mansoni

Schistosomiasis affects over 200 million people worldwide, with over 200,000 deaths annually. Currently, praziquantel is the only drug available against schistosomiasis. We report here that Schistosoma mansoni farnesyl diphosphate synthase (SmFPPS) and geranylgeranyl diphosphate synthase (SmGGPPS) a...

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Detalhes bibliográficos
Main Authors: Ziniel, Peter D., Desai, Janish, Cass, Cynthia L., Gatto, Craig, Oldfield, Eric, Williams, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837879/
https://ncbi.nlm.nih.gov/pubmed/24041901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00699-13
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