Characterization of Potential Drug Targets Farnesyl Diphosphate Synthase and Geranylgeranyl Diphosphate Synthase in Schistosoma mansoni

Schistosomiasis affects over 200 million people worldwide, with over 200,000 deaths annually. Currently, praziquantel is the only drug available against schistosomiasis. We report here that Schistosoma mansoni farnesyl diphosphate synthase (SmFPPS) and geranylgeranyl diphosphate synthase (SmGGPPS) a...

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Autors principals: Ziniel, Peter D., Desai, Janish, Cass, Cynthia L., Gatto, Craig, Oldfield, Eric, Williams, David L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837879/
https://ncbi.nlm.nih.gov/pubmed/24041901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00699-13
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