Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum

BACKGROUND: Isoprenoids are the most diverse and abundant group of natural products. In Plasmodium falciparum, isoprenoid synthesis proceeds through the methyl erythritol diphosphate pathway and the products are further metabolized by farnesyl diphosphate synthase (FPPS), turning this enzyme into a...

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Hauptverfasser: Jordão, Fabiana M, Gabriel, Heloisa B, Alves, João MP, Angeli, Claudia B, Bifano, Thaís D, Breda, Ardala, de Azevedo, Mauro F, Basso, Luiz A, Wunderlich, Gerhard, Kimura, Emilia A, Katzin, Alejandro M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679732/
https://ncbi.nlm.nih.gov/pubmed/23734739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-184
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