Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum

BACKGROUND: Isoprenoids are the most diverse and abundant group of natural products. In Plasmodium falciparum, isoprenoid synthesis proceeds through the methyl erythritol diphosphate pathway and the products are further metabolized by farnesyl diphosphate synthase (FPPS), turning this enzyme into a...

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Detalhes bibliográficos
Main Authors: Jordão, Fabiana M, Gabriel, Heloisa B, Alves, João MP, Angeli, Claudia B, Bifano, Thaís D, Breda, Ardala, de Azevedo, Mauro F, Basso, Luiz A, Wunderlich, Gerhard, Kimura, Emilia A, Katzin, Alejandro M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679732/
https://ncbi.nlm.nih.gov/pubmed/23734739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-184
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