Characterization of Potential Drug Targets Farnesyl Diphosphate Synthase and Geranylgeranyl Diphosphate Synthase in Schistosoma mansoni

Schistosomiasis affects over 200 million people worldwide, with over 200,000 deaths annually. Currently, praziquantel is the only drug available against schistosomiasis. We report here that Schistosoma mansoni farnesyl diphosphate synthase (SmFPPS) and geranylgeranyl diphosphate synthase (SmGGPPS) a...

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Main Authors: Ziniel, Peter D., Desai, Janish, Cass, Cynthia L., Gatto, Craig, Oldfield, Eric, Williams, David L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837879/
https://ncbi.nlm.nih.gov/pubmed/24041901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00699-13
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