Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

Drug combinations are valuable tools for studying biological systems. Although much attention has been given to synergistic interactions in revealing connections between cellular processes, antagonistic interactions can also have tremendous value in elucidating genetic networks and mechanisms of dru...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Farha, Maya A., Czarny, Tomasz L., Myers, Cullen L., Worrall, Liam J., French, Shawn, Conrady, Deborah G., Wang, Yang, Oldfield, Eric, Strynadka, Natalie C. J., Brown, Eric D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568241/
https://ncbi.nlm.nih.gov/pubmed/26283394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511751112
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