Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

Drug combinations are valuable tools for studying biological systems. Although much attention has been given to synergistic interactions in revealing connections between cellular processes, antagonistic interactions can also have tremendous value in elucidating genetic networks and mechanisms of dru...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Farha, Maya A., Czarny, Tomasz L., Myers, Cullen L., Worrall, Liam J., French, Shawn, Conrady, Deborah G., Wang, Yang, Oldfield, Eric, Strynadka, Natalie C. J., Brown, Eric D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568241/
https://ncbi.nlm.nih.gov/pubmed/26283394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511751112
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