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Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth

We synthesized potential inhibitors of farnesyl diphosphate synthase (FPPS), undecaprenyl diphosphate synthase (UPPS) or undecaprenyl diphosphate phosphatase (UPPP), and tested them in bacterial cell growth and enzyme inhibition assays. The most active compounds were bisphosphonates with electron-wi...

詳細記述

保存先:
書誌詳細
出版年:ChemMedChem
主要な著者: Desai, Janish, Wang, Yang, Wang, Ke, Malwal, Satish R., Oldfield, Eric
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160999/
https://ncbi.nlm.nih.gov/pubmed/27571880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600343
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