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Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth
We synthesized potential inhibitors of farnesyl diphosphate synthase (FPPS), undecaprenyl diphosphate synthase (UPPS) or undecaprenyl diphosphate phosphatase (UPPP), and tested them in bacterial cell growth and enzyme inhibition assays. The most active compounds were bisphosphonates with electron-wi...
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| Foilsithe in: | ChemMedChem |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5160999/ https://ncbi.nlm.nih.gov/pubmed/27571880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600343 |
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