Engineering unnatural variants of plantazolicin through codon reprogramming

Por Deane, Caitlin D., Melby, Joel O., Molohon, Katie J., Susarrey, Aziz R., Mitchell, Douglas A.
Publicado em 2013

Plantazolicin, a Novel Microcin B17/Streptolysin S-Like Natural Product from Bacillus amyloliquefaciens FZB42

Por Scholz, Romy, Molohon, Katie J., Nachtigall, Jonny, Vater, Joachim, Markley, Andrew L., Süssmuth, Roderich D., Mitchell, Douglas A., Borriss, Rainer
Publicado em 2011

Structure Determination and Interception of Biosynthetic Intermediates for the Plantazolicin Class of Highly Discriminating Antibiotics

Por Molohon, Katie J., Melby, Joel O., Lee, Jaeheon, Evans, Bradley S., Dunbar, Kyle L., Bumpus, Stefanie B., Kelleher, Neil L., Mitchell, Douglas A.
Publicado em 2011

Plantazolicin is an ultra-narrow spectrum antibiotic that targets the Bacillus anthracis membrane

Por Molohon, Katie J., Blair, Patricia M., Park, Seongjin, Doroghazi, James R., Maxson, Tucker, Hershfield, Jeremy R., Flatt, Kristen M., Schroeder, Nathan E., Ha, Taekjip, Mitchell, Douglas A.
Publicado no ACS Infect Dis (2015)

HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis

Por Zhang, Yonghui, Lin, Fu-Yang, Li, Kai, Zhu, Wei, Liu, Yi-Liang, Cao, Rong, Pang, Ran, Lee, Eunhae, Axelson, Jordan, Hensler, Mary, Wang, Ke, Molohon, Katie J., Wang, Yang, Mitchell, Douglas A., Nizet, Victor, Oldfield, Eric
Publicado em 2012

Antibacterial drug leads targeting isoprenoid biosynthesis

Por Zhu, Wei, Zhang, Yonghui, Sinko, William, Hensler, Mary E., Olson, Joshua, Molohon, Katie J., Lindert, Steffen, Cao, Rong, Li, Kai, Wang, Ke, Wang, Yang, Liu, Yi-Liang, Sankovsky, Anna, de Oliveira, César Augusto F., Mitchell, Douglas A., Nizet, Victor, McCammon, J. Andrew, Oldfield, Eric
Publicado em 2013

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

Por Li, Kai, Schurig-Briccio, Lici A., Feng, Xinxin, Upadhyay, Ashutosh, Pujari, Venugopal, Lechartier, Benoit, Fontes, Fabio L., Yang, Hongliang, Rao, Guodong, Zhu, Wei, Gulati, Anmol, No, Joo Hwan, Cintra, Giovana, Bogue, Shannon, Liu, Yi-Liang, Molohon, Katie, Orlean, Peter, Mitchell, Douglas A., Freitas-Junior, Lucio, Ren, Feifei, Sun, Hong, Jiang, Tong, Li, Yujie, Guo, Rey-Ting, Cole, Stewart T., Gennis, Robert B., Crick, Dean C., Oldfield, Eric
Publicado em 2014