Membrane phospholipid synthesis and endoplasmic reticulum function

Por Fagone, Paolo, Jackowski, Suzanne
Publicado em 2009

Phosphatidylcholine and the CDP-Choline Cycle

Por Fagone, Paolo, Jackowski, Suzanne
Publicado em 2012

CTP:Phosphocholine Cytidylyltransferase α Is Required for B-cell Proliferation and Class Switch Recombination

Por Fagone, Paolo, Gunter, Christopher, Sage, Christopher R., Gunn, Kathryn E., Brewer, Joseph W., Jackowski, Suzanne
Publicado em 2009

Systemic Errors in Quantitative Polymerase Chain Reaction Titration of Self-Complementary Adeno-Associated Viral Vectors and Improved Alternative Methods

Por Fagone, Paolo, Wright, J. Fraser, Nathwani, Amit C., Nienhuis, Arthur W., Davidoff, Andrew M., Gray, John T.
Publicado em 2012

Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice

Por Shumar, Stephanie A., Fagone, Paolo, Alfonso-Pecchio, Adolfo, Gray, John T., Rehg, Jerold E., Jackowski, Suzanne, Leonardi, Roberta
Publicado no PLoS One (2015)

17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease

Por Nicoletti, Ferdinando, Philippens, Ingrid, Fagone, Paolo, Ahlem, Clarence N., Reading, Christopher L., Frincke, James M., Auci, Dominick L.
Publicado em 2012

BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer

Por Donia, Marco, Fagone, Paolo, Nicoletti, Ferdinando, Andersen, Rikke Sick, Høgdall, Estrid, Straten, Per thor, Andersen, Mads Hald, Svane, Inge Marie
Publicado em 2012

VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus

Por Fagone, Paolo, Muthumani, Karuppiah, Mangano, Katia, Magro, Gaetano, Meroni, Pier Luigi, Kim, Joseph J, Sardesai, Niranjan Y, Weiner, David B, Nicoletti, Ferdinando
Publicado em 2014

ATF6α induces XBP1-independent expansion of the endoplasmic reticulum

Por Bommiasamy, Hemamalini, Back, Sung Hoon, Fagone, Paolo, Lee, Kyungho, Meshinchi, Sasha, Vink, Elizabeth, Sriburi, Rungtawan, Frank, Matthew, Jackowski, Suzanne, Kaufman, Randal J., Brewer, Joseph W.
Publicado em 2009

Identification of novel chemotherapeutic strategies for metastatic uveal melanoma

Por Fagone, Paolo, Caltabiano, Rosario, Russo, Andrea, Lupo, Gabriella, Anfuso, Carmelina Daniela, Basile, Maria Sofia, Longo, Antonio, Nicoletti, Ferdinando, De Pasquale, Rocco, Libra, Massimo, Reibaldi, Michele
Publicado no Sci Rep (2017)

Co-immunization with an optimized plasmid-encoded immune stimulatory interleukin, high-mobility group box 1 protein, results in enhanced interferon-γ secretion by antigen-specific...

Por Muthumani, Gowtham, Laddy, Dominick J, Sundaram, Senthil G, Fagone, Paolo, Shedlock, Devon J, Kannan, Senthil, Wu, Ling, Chung, Christopher W, Lankaraman, Karthikbabu Mallil, Burns, John, Muthumani, Karuppiah, Weiner, David B
Publicado em 2009

Good Manufacturing Practice Production of Self-Complementary Serotype 8 Adeno-Associated Viral Vector for a Hemophilia B Clinical Trial

Por Allay, James A., Sleep, Susan, Long, Scott, Tillman, David M., Clark, Rob, Carney, Gael, Fagone, Paolo, McIntosh, Jenny H., Nienhuis, Arthur W., Davidoff, Andrew M., Nathwani, Amit C., Gray, John T.
Publicado em 2011

HIV mediated PI3K/Akt activation in antigen presenting cells leads to PD-1 ligand upregulation and suppression of HIV specific CD8 T-cells

Por Muthumani, Karuppiah, Shedlock, Devon J., Choo, Daniel K., Fagone, Paolo, Kawalekar, Omkar U., Goodman, Jonathan, Bian, Chaoran B., Ramanathan, Aarti A., Atman, Parikh, Tebas, Pablo, Chattergoon, Michael A., Choo, Andrew Y., Weiner, David B.
Publicado em 2011

A DNA Vaccine against Chikungunya Virus Is Protective in Mice and Induces Neutralizing Antibodies in Mice and Nonhuman Primates

Por Mallilankaraman, Karthik, Shedlock, Devon J., Bao, Huihui, Kawalekar, Omkar U., Fagone, Paolo, Ramanathan, Aarthi A., Ferraro, Bernadette, Stabenow, Jennifer, Vijayachari, Paluru, Sundaram, Senthil G., Muruganandam, Nagarajan, Sarangan, Gopalsamy, Srikanth, Padma, Khan, Amir S., Lewis, Mark G., Kim, J. Joseph, Sardesai, Niranjan Y., Muthumani, Karuppiah, Weiner, David B.
Publicado em 2011

Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response

Por McCubrey, James A., Steelman, Linda S., Chappell, William H., Abrams, Stephen L., Montalto, Giuseppe, Cervello, Melchiorre, Nicoletti, Ferdinando, Fagone, Paolo, Malaponte, Grazia, Mazzarino, Maria C., Candido, Saverio, Libra, Massimo, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Cocco, Lucio, Evangelisti, Camilla, Chiarini, Francesca, Martelli, Alberto M.
Publicado em 2012

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

Por McCubrey, James A., Steelman, Linda S., Chappell, William H., Abrams, Stephen L., Franklin, Richard A., Montalto, Giuseppe, Cervello, Melchiorre, Libra, Massimo, Candido, Saverio, Malaponte, Grazia, Mazzarino, Maria C., Fagone, Paolo, Nicoletti, Ferdinando, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Chiarini, Francesca, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M.
Publicado em 2012

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

Por Steelman, Linda S., Chappell, William H., Abrams, Stephen L., Kempf, C. Ruth, Long, Jacquelyn, Laidler, Piotr, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Stivala, Franca, Mazzarino, Maria C., Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Nicoletti, Ferdinando, Libra, Massimo, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Bäsecke, Jörg, Cocco, Lucio, Evangelisti, Camilla, Martelli, Alberto M., Montalto, Giuseppe, Cervello, Melchiorre, McCubrey, James A.
Publicado em 2011

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health

Por Chappell, William H., Steelman, Linda S., Long, Jacquelyn M., Kempf, Ruth C., Abrams, Stephen L., Franklin, Richard A., Bäsecke, Jörg, Stivala, Franca, Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Mazzarino, Maria C., Nicoletti, Ferdinando, Libra, Massimo, Maksimovic-Ivanic, Danijela, Mijatovic, Sanja, Montalto, Giuseppe, Cervello, Melchiorre, Laidler, Piotr, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M., McCubrey, James A.
Publicado em 2011

Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

Por McIntosh, Jenny, Lenting, Peter J., Rosales, Cecilia, Lee, Doyoung, Rabbanian, Samira, Raj, Deepak, Patel, Nishil, Tuddenham, Edward G. D., Christophe, Olivier D., McVey, John H., Waddington, Simon, Nienhuis, Arthur W., Gray, John T., Fagone, Paolo, Mingozzi, Federico, Zhou, Shang-Zhen, High, Katherine A., Cancio, Maria, Ng, Catherine Y. C., Zhou, Junfang, Morton, Christopher L., Davidoff, Andrew M., Nathwani, Amit C.
Publicado em 2013

Advances in Targeting Signal Transduction Pathways

Por McCubrey, James A., Steelman, Linda S., Chappell, William H., Sun, Lin, Davis, Nicole M., Abrams, Stephen L., Franklin, Richard A., Cocco, Lucio, Evangelisti, Camilla, Chiarini, Francesca, Martelli, Alberto M., Libra, Massimo, Candido, Saverio, Ligresti, Giovanni, Malaponte, Grazia, Mazzarino, Maria C., Fagone, Paolo, Donia, Marco, Nicoletti, Ferdinando, Polesel, Jerry, Talamini, Renato, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Dulińska-Litewka, Joanna, Laidler, Piotr, D'Assoro, Antonio B., Drobot, Lyudmyla, Umezawa, Kazuo, Montalto, Giuseppe, Cervello, Melchiorre, Demidenko, Zoya N.
Publicado em 2012