HIV mediated PI3K/Akt activation in antigen presenting cells leads to PD-1 ligand upregulation and suppression of HIV specific CD8 T-cells

Recent evidence demonstrates that HIV-1 infection leads to the attenuation of cellular immune responses, which has been correlated with the increased expression of programmed death 1 (PD-1) on virus-specific CD8(+) T cells. PD-1 is induced upon T cell activation and its prolonged expression facilita...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Muthumani, Karuppiah, Shedlock, Devon J., Choo, Daniel K., Fagone, Paolo, Kawalekar, Omkar U., Goodman, Jonathan, Bian, Chaoran B., Ramanathan, Aarti A., Atman, Parikh, Tebas, Pablo, Chattergoon, Michael A., Choo, Andrew Y., Weiner, David B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197696/
https://ncbi.nlm.nih.gov/pubmed/21856939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100594
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