Phosphoinositide-specific phospholipase C in health and disease

Por Cocco, Lucio, Follo, Matilde Y., Manzoli, Lucia, Suh, Pann-Ghill
Publicado no J Lipid Res (2015)

K562 cell proliferation is modulated by PLCβ1 through a PKCα-mediated pathway

Por Poli, Alessandro, Faenza, Irene, Chiarini, Francesca, Matteucci, Alessandro, McCubrey, James A., Cocco, Lucio
Publicado em 2013

Phosphoinositide-specific Phospholipase C β 1b (PI-PLCβ1b) Interactome: Affinity Purification-Mass Spectrometry Analysis of PI-PLCβ1b with Nuclear Protein

Por Piazzi, Manuela, Blalock, William L., Bavelloni, Alberto, Faenza, Irene, D'Angelo, Antonietta, Maraldi, Nadir M., Cocco, Lucio
Publicado em 2013

The therapeutic potential of mTOR inhibitors in breast cancer

Por Steelman, Linda S., Martelli, Alberto M., Cocco, Lucio, Libra, Massimo, Nicoletti, Ferdinando, Abrams, Stephen L., McCubrey, James A.
Publicado no Br J Clin Pharmacol (2016)

Phosphorylation of Nuclear Phospholipase C β1 by Extracellular Signal-Regulated Kinase Mediates the Mitogenic Action of Insulin-Like Growth Factor I

Por Xu, Aimin, Suh, Pann-Ghill, Marmy-Conus, Nelly, Pearson, Richard B., Seok, Oh Yong, Cocco, Lucio, Gilmour, R. Stewart
Publicado em 2001

Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)

Por Cenni, Vittoria, Bavelloni, Alberto, Beretti, Francesca, Tagliavini, Francesca, Manzoli, Lucia, Lattanzi, Giovanna, Maraldi, Nadir M., Cocco, Lucio, Marmiroli, Sandra
Publicado em 2011

A novel DAG-dependent mechanism links PKCa and Cyclin B1 regulating cell cycle progression

Por Poli, Alessandro, Ramazzotti, Giulia, Matteucci, Alessandro, Manzoli, Lucia, Lonetti, Annalisa, Suh, Pann-Ghill, McCubrey, James A., Cocco, Lucio
Publicado no Oncotarget (2014)

PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells

Por Bavelloni, Alberto, Poli, Alessandro, Fiume, Roberta, Blalock, William, Matteucci, Alessandro, Ramazzotti, Giulia, McCubrey, James A., Cocco, Lucio, Faenza, Irene
Publicado em 2014

Quantitative profiling of the endonuclear glycerophospholipidome of murine embryonic fibroblasts

Por Tribble, Emily K., Ivanova, Pavlina T., Grabon, Aby, Alb, James G., Faenza, Irene, Cocco, Lucio, Brown, H. Alex, Bankaitis, Vytas A.
Publicado no J Lipid Res (2016)

eEF1A Phosphorylation in the Nucleus of Insulin-stimulated C2C12 Myoblasts: SER(53) IS A NOVEL SUBSTRATE FOR PROTEIN KINASE C βI

Por Piazzi, Manuela, Bavelloni, Alberto, Faenza, Irene, Blalock, William, Urbani, Andrea, D'Aguanno, Simona, Fiume, Roberta, Ramazzotti, Giulia, Maraldi, Nadir Mario, Cocco, Lucio
Publicado em 2010

Quantitative phosphoproteome analysis of embryonic stem cell differentiation toward blood

Por Piazzi, Manuela, Williamson, Andrew, Lee, Chia-Fang, Pearson, Stella, Lacaud, Georges, Kouskoff, Valerie, McCubrey, James A., Cocco, Lucio, Whetton, Anthony D.
Publicado no Oncotarget (2015)

IPMK and β-catenin mediate PLC-β1-dependent signaling in myogenic differentiation

Por Ramazzotti, Giulia, Billi, Anna Maria, Manzoli, Lucia, Mazzetti, Cristina, Ruggeri, Alessandra, Erneux, Christophe, Kim, Seyun, Suh, Pann-Ghill, Cocco, Lucio, Faenza, Irene
Publicado no Oncotarget (2016)

Nuclear phospholipase C isoenzyme imbalance leads to pathologies in brain, hematologic, neuromuscular, and fertility disorders

Por Ratti, Stefano, Follo, Matilde Y., Ramazzotti, Giulia, Faenza, Irene, Fiume, Roberta, Suh, Pann-Ghill, McCubrey, James A., Manzoli, Lucia, Cocco, Lucio
Publicado no J Lipid Res (2019)

Phosphoinositide 3 Kinase Signaling in Human Stem Cells from Reprogramming to Differentiation: A Tale in Cytoplasmic and Nuclear Compartments

Por Ramazzotti, Giulia, Ratti, Stefano, Fiume, Roberta, Follo, Matilde Yung, Billi, Anna Maria, Rusciano, Isabella, Owusu Obeng, Eric, Manzoli, Lucia, Cocco, Lucio, Faenza, Irene
Publicado no Int J Mol Sci (2019)

Proapoptotic Activity and Chemosensitizing Effect of the Novel Akt Inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-Cell...

Por Falà, Federica, Blalock, William L., Tazzari, Pier Luigi, Cappellini, Alessandra, Chiarini, Francesca, Martinelli, Giovanni, Tafuri, Agostino, McCubrey, James A., Cocco, Lucio, Martelli, Alberto M.
Publicado em 2008

Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression

Por Steelman, Linda S., Abrams, Steve L., Ruvolo, Peter, Ruvolo, Vivian, Cocco, Lucio, Ratti, Stefano, Martelli, Alberto M., Neri, Luca M., Candido, Saverio, Libra, Massimo, McCubrey, James A.
Publicado no Oncotarget (2017)

SYNERGISTIC PROAPOPTOTIC ACTIVITY OF RECOMBINANT TRAIL PLUS THE AKT INHIBITOR PERIFOSINE IN ACUTE MYELOGENOUS LEUKEMIA CELLS

Por Tazzari, Pier Luigi, Tabellini, Giovanna, Ricci, Francesca, Papa, Veronica, Bortul, Roberta, Chiarini, Francesca, Evangelisti, Camilla, Martinelli, Giovanni, Bontadini, Andrea, Cocco, Lucio, McCubrey, James A., Martelli, Alberto M.
Publicado em 2008

Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS

Por Follo, Matilde Y., Finelli, Carlo, Mongiorgi, Sara, Clissa, Cristina, Bosi, Costanza, Testoni, Nicoletta, Chiarini, Francesca, Ramazzotti, Giulia, Baccarani, Michele, Martelli, Alberto M., Manzoli, Lucia, Martinelli, Giovanni, Cocco, Lucio
Publicado em 2009

Netrin‐1/DCC‐mediated PLCγ1 activation is required for axon guidance and brain structure development

Por Kang, Du‐Seock, Yang, Yong Ryoul, Lee, Cheol, Park, BumWoo, Park, Kwang Il, Seo, Jeong Kon, Seo, Young Kyo, Cho, HyungJoon, Cocco, Lucio, Suh, Pann‐Ghill
Publicado no EMBO Rep (2019)

Phosphoinositide-Dependent Signaling in Cancer: A Focus on Phospholipase C Isozymes

Por Owusu Obeng, Eric, Rusciano, Isabella, Marvi, Maria Vittoria, Fazio, Antonietta, Ratti, Stefano, Follo, Matilde Yung, Xian, Jie, Manzoli, Lucia, Billi, Anna Maria, Mongiorgi, Sara, Ramazzotti, Giulia, Cocco, Lucio
Publicado no Int J Mol Sci (2020)