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A novel DAG-dependent mechanism links PKCa and Cyclin B1 regulating cell cycle progression

Through the years, different studies showed the involvement of Protein Kinase C (PKC) in cell cycle control, in particular during G1/S transition. Little is known about their role at G2/M checkpoint. In this study, using K562 human erythroleukemia cell line, we found a novel and specific mechanism t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Poli, Alessandro, Ramazzotti, Giulia, Matteucci, Alessandro, Manzoli, Lucia, Lonetti, Annalisa, Suh, Pann-Ghill, McCubrey, James A., Cocco, Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294327/
https://ncbi.nlm.nih.gov/pubmed/25362646
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