Involvement of Akt-1 and mTOR in Sensitivity of Breast Cancer to Targeted Therapy

Por Sokolosky, Melissa L., Stadelman, Kristin M., Chappell, William H., Abrams, Stephen L., Martelli, Alberto M., Stivala, Franca, Libra, Massimo, Nicoletti, Ferdinando, Drobot, Lyudmyla B., Franklin, Richard A., Steelman, Linda S., McCubrey, James A.
Publicado em 2011

Targeting the RAF/MEK/ERK, PI3K/AKT and P53 pathways in hematopoietic drug resistance

Por McCubrey, James A., Steelman, Linda S., Franklin, Richard A., Abrams, Steven L., Chappell, William H., Wong, Ellis WT, Lehmann, Brian, Terrian, David M., Basecke, Jorg, Stivala, Franca, Libra, Massimo, Evangelisti, Camilla, Martelli, Alberto M.
Publicado em 2007

Involvement of Akt and mTOR in chemotherapeutic and hormonal-based drug resistance and response to radiation in breast cancer cells

Por Steelman, Linda S, Navolanic, Patrick, Chappell, William H, Abrams, Stephen L, Wong, Ellis WT, Martelli, Alberto M, Cocco, Lucio, Stivala, Franca, Libra, Massimo, Nicoletti, Ferdinando, Drobot, Lyudmyla B, Franklin, Richard A, McCubrey, James A
Publicado em 2011

ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE

Por McCubrey, James A., Steelman, Linda S., Chappell, William H., Abrams, Steven L., Wong, Ellis WT., Chang, Fumin, Lehmann, Brian, Terrian, David M., Milella, Michele, Tafuri, Agostino, Stivala, Franca, Libra, Massimo, Basecke, Jorg, Evangelisti, Camilla, Martelli, Alberto M., Franklin, Richard A.
Publicado em 2006

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine

Por Chappell, William H., Abrams, Stephen L., Franklin, Richard A., LaHair, Michelle M., Montalto, Giuseppe, Cervello, Melchiorre, Martelli, Alberto M., Nicoletti, Ferdinando, Candido, Saverio, Libra, Massimo, Polesel, Jerry, Talamini, Renato, Milella, Michele, Tafuri, Agostino, Steelman, Linda S., McCubrey, James A.
Publicado em 2012

Suppression of PTEN Function Increases Breast Cancer Chemotherapeutic Drug Resistance while Conferring Sensitivity to mTOR Inhibitors

Por Steelman, Linda S., Navolanic, Patrick M., Sokolosky, Melissa L., Taylor, Jackson R., Lehmann, Brian D., Chappell, William H., Abrams, Steven L., Wong, Ellis W.T., Stadelman, Kristin M., Terrian, David M., Leslie, Nick R., Martelli, C. Alberto M., Stivala, Franca, Libra, Massimo, Franklin, Richard A., McCubrey, James A.
Publicado em 2008

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

Por McCubrey, James A., Steelman, Linda S., Chappell, William H., Abrams, Stephen L., Franklin, Richard A., Montalto, Giuseppe, Cervello, Melchiorre, Libra, Massimo, Candido, Saverio, Malaponte, Grazia, Mazzarino, Maria C., Fagone, Paolo, Nicoletti, Ferdinando, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Chiarini, Francesca, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M.
Publicado em 2012

ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY

Por McCubrey, James A., Sokolosky, Melissa L., Lehmann, Brian D., Taylor, Jackson R., Navolanic, Patrick M., Chappell, William H., Abrams, Stephen L., Stadelman, Kristin M., Wong, Ellis WT, Misaghian, Negin, Horn, Stefan, Bäsecke, Jörg, Libra, Massimo, Stivala, Franca, Ligresti, Giovanni, Tafuri, Agostino, Milella, Michele, Zarzycki, Marek, Dzugaj, Andrzej, Chiarini, Francesca, Evangelisti, Camilla, Martelli, Alberto M., Terrian, David M., Franklin, Richard A., Steelman, Linda S.
Publicado em 2008

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health

Por Chappell, William H., Steelman, Linda S., Long, Jacquelyn M., Kempf, Ruth C., Abrams, Stephen L., Franklin, Richard A., Bäsecke, Jörg, Stivala, Franca, Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Mazzarino, Maria C., Nicoletti, Ferdinando, Libra, Massimo, Maksimovic-Ivanic, Danijela, Mijatovic, Sanja, Montalto, Giuseppe, Cervello, Melchiorre, Laidler, Piotr, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M., McCubrey, James A.
Publicado em 2011

Advances in Targeting Signal Transduction Pathways

Por McCubrey, James A., Steelman, Linda S., Chappell, William H., Sun, Lin, Davis, Nicole M., Abrams, Stephen L., Franklin, Richard A., Cocco, Lucio, Evangelisti, Camilla, Chiarini, Francesca, Martelli, Alberto M., Libra, Massimo, Candido, Saverio, Ligresti, Giovanni, Malaponte, Grazia, Mazzarino, Maria C., Fagone, Paolo, Donia, Marco, Nicoletti, Ferdinando, Polesel, Jerry, Talamini, Renato, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Dulińska-Litewka, Joanna, Laidler, Piotr, D'Assoro, Antonio B., Drobot, Lyudmyla, Umezawa, Kazuo, Montalto, Giuseppe, Cervello, Melchiorre, Demidenko, Zoya N.
Publicado em 2012