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VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus

VGX-1027 [(S,R)-3-phenyl-4,5-dihydro-5-isoxasole acetic acid] is a small molecule compound with immunomodulatory properties, which favourably influences the development of immuno-inflammatory and autoimmune diseases in different animal models such as type 1 diabetes mellitus, pleurisy, rheumatoid ar...

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Hlavní autoři: Fagone, Paolo, Muthumani, Karuppiah, Mangano, Katia, Magro, Gaetano, Meroni, Pier Luigi, Kim, Joseph J, Sardesai, Niranjan Y, Weiner, David B, Nicoletti, Ferdinando
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107669/
https://ncbi.nlm.nih.gov/pubmed/24527796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12267
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