CTP:Phosphocholine Cytidylyltransferase α Is Required for B-cell Proliferation and Class Switch Recombination

CTP:phosphocholine cytidylyltransferase (CCT) is a key rate-controlling enzyme in the biosynthetic pathway leading to the principle membrane phospholipid, phosphatidylcholine. CCTα is the predominant isoform expressed in mammalian cells. To investigate the role of CCTα in the development and functio...

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Main Authors: Fagone, Paolo, Gunter, Christopher, Sage, Christopher R., Gunn, Kathryn E., Brewer, Joseph W., Jackowski, Suzanne
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
主題:
Membrane Transport, Structure, Function, and Biogenesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652266/
https://ncbi.nlm.nih.gov/pubmed/19139091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807338200
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