CTP:Phosphocholine Cytidylyltransferase α Is Required for B-cell Proliferation and Class Switch Recombination

CTP:phosphocholine cytidylyltransferase (CCT) is a key rate-controlling enzyme in the biosynthetic pathway leading to the principle membrane phospholipid, phosphatidylcholine. CCTα is the predominant isoform expressed in mammalian cells. To investigate the role of CCTα in the development and functio...

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Библиографические подробности
Главные авторы: Fagone, Paolo, Gunter, Christopher, Sage, Christopher R., Gunn, Kathryn E., Brewer, Joseph W., Jackowski, Suzanne
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Membrane Transport, Structure, Function, and Biogenesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652266/
https://ncbi.nlm.nih.gov/pubmed/19139091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807338200
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