CTP:Phosphocholine Cytidylyltransferase α Is Required for B-cell Proliferation and Class Switch Recombination

CTP:phosphocholine cytidylyltransferase (CCT) is a key rate-controlling enzyme in the biosynthetic pathway leading to the principle membrane phospholipid, phosphatidylcholine. CCTα is the predominant isoform expressed in mammalian cells. To investigate the role of CCTα in the development and functio...

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Autori principali: Fagone, Paolo, Gunter, Christopher, Sage, Christopher R., Gunn, Kathryn E., Brewer, Joseph W., Jackowski, Suzanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Membrane Transport, Structure, Function, and Biogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652266/
https://ncbi.nlm.nih.gov/pubmed/19139091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807338200
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