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Probucol Therapy Overcomes the Reproductive Defect in CTP:Phosphocholine Cytidylyltransferase β2 Knockout Mice
The synthesis of phosphatidylcholine (PtdCho), the major phospholipid in mammalian cells, is regulated by the CTP:phosphocholine cytidylyltransferase (CCT). Loss of the CCTβ2 isoform expression in mice results in gonadal dysfunction. CCTβ2(−/−) females exhibit ovarian tissue disorganization with pro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950155/ https://ncbi.nlm.nih.gov/pubmed/17560827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2007.04.015 |
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