PET and SPECT Radiotracers to Assess Function and Expression of ABC Transporters in Vivo

Por Mairinger, Severin, Erker, Thomas, Müller, Markus, Langer, Oliver
Publicado em 2011

Structure–activity relationships of bumetanide derivatives: correlation between diuretic activity in dogs and inhibition of the human NKCC2A transporter

Por Lykke, Kasper, Töllner, Kathrin, Römermann, Kerstin, Feit, Peter W, Erker, Thomas, MacAulay, Nanna, Löscher, Wolfgang
Publicado no Br J Pharmacol (2015)

Drug trapping in hERG K(+) channels: (not) a matter of drug size?

Por Linder, Tobias, Bernsteiner, Harald, Saxena, Priyanka, Bauer, Florian, Erker, Thomas, Timin, Eugen, Hering, Steffen, Stary-Weinzinger, Anna
Publicado no Medchemcomm (2016)

Foam Cell Specific LXRα Ligand

Por Feldmann, Radmila, Geikowski, Anne, Weidner, Christopher, Witzke, Annabell, Kodelja, Vitam, Schwarz, Thomas, Gabriel, Mario, Erker, Thomas, Sauer, Sascha
Publicado em 2013

Resveratrol blocks Akt activation in angiotensin II- or EGF-stimulated vascular smooth muscle cells in a redox-independent manner

Por Schreiner, Cornelia E., Kumerz, Mario, Gesslbauer, Julia, Schachner, Daniel, Joa, Helge, Erker, Thomas, Atanasov, Atanas G., Heiss, Elke H., Dirsch, Verena M.
Publicado em 2011

Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomography

Por Bauer, Florian, Wanek, Thomas, Mairinger, Severin, Stanek, Johann, Sauberer, Michael, Kuntner, Claudia, Parveen, Zahida, Chiba, Peter, Müller, Markus, Langer, Oliver, Erker, Thomas
Publicado em 2012

GABA(A) receptor modulation by piperine and a non-TRPV1 activating derivative()

Por Khom, Sophia, Strommer, Barbara, Schöffmann, Angela, Hintersteiner, Juliane, Baburin, Igor, Erker, Thomas, Schwarz, Thomas, Schwarzer, Christoph, Zaugg, Janine, Hamburger, Matthias, Hering, Steffen
Publicado em 2013

Novel Promising Estrogenic Receptor Modulators: Cytotoxic and Estrogenic Activity of Benzanilides and Dithiobenzanilides

Por Kucinska, Malgorzata, Giron, Maria-Dolores, Piotrowska, Hanna, Lisiak, Natalia, Granig, Walter H., Lopez-Jaramillo, Francisco-Javier, Salto, Rafael, Murias, Marek, Erker, Thomas
Publicado no PLoS One (2016)

Small-animal PET evaluation of [(11)C]MC113 as a PET tracer for P-glycoprotein

Por Mairinger, Severin, Colabufo, Nicola A, Wanek, Thomas, Kuntner, Claudia, Stanek, Johann, Erker, Thomas, Cantore, Mariangela, Berardi, Francesco, Perrone, Roberto, Müller, Markus, Langer, Oliver
Publicado em 2010

The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study

Por Mairinger, Severin, Bankstahl, Jens P., Kuntner, Claudia, Römermann, Kerstin, Bankstahl, Marion, Wanek, Thomas, Stanek, Johann, Löscher, Wolfgang, Müller, Markus, Erker, Thomas, Langer, Oliver
Publicado em 2012

A novel PET protocol for visualization of breast cancer resistance protein function at the blood–brain barrier

Por Wanek, Thomas, Kuntner, Claudia, Bankstahl, Jens P, Mairinger, Severin, Bankstahl, Marion, Stanek, Johann, Sauberer, Michael, Filip, Thomas, Erker, Thomas, Müller, Markus, Löscher, Wolfgang, Langer, Oliver
Publicado em 2012

Synthesis and in vivo evaluation of [(11)C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor

Por Bauer, Florian, Kuntner, Claudia, Bankstahl, Jens P., Wanek, Thomas, Bankstahl, Marion, Stanek, Johann, Mairinger, Severin, Dörner, Bernd, Löscher, Wolfgang, Müller, Markus, Erker, Thomas, Langer, Oliver
Publicado em 2010

Synthesis and small-animal positron emission tomography evaluation of [(11)C]-elacridar as a radiotracer to assess the distribution of P-glycoprotein at the blood-brain barrier

Por Dörner, Bernd, Kuntner, Claudia, Bankstahl, Jens P., Bankstahl, Marion, Stanek, Johann, Wanek, Thomas, Stundner, Gloria, Mairinger, Severin, Löscher, Wolfgang, Müller, Markus, Langer, Oliver, Erker, Thomas
Publicado em 2009

A comparative small-animal PET evaluation of [(11)C]tariquidar, [(11)C]elacridar and (R)-[(11)C]verapamil for detection of P-glycoprotein expressing murine breast cancer

Por Wanek, Thomas, Kuntner, Claudia, Bankstahl, Jens P., Bankstahl, Marion, Stanek, Johann, Sauberer, Michael, Mairinger, Severin, Strommer, Sabine, Wacheck, Volker, Löscher, Wolfgang, Erker, Thomas, Müller, Markus, Langer, Oliver
Publicado em 2011

Synthesis and in vivo evaluation of the putative breast cancer resistance protein inhibitor [(11)C]methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)am...

Por Mairinger, Severin, Langer, Oliver, Kuntner, Claudia, Wanek, Thomas, Bankstahl, Jens P., Bankstahl, Marion, Stanek, Johann, Dörner, Bernd, Bauer, Florian, Baumgartner, Christoph, Löscher, Wolfgang, Erker, Thomas, Müller, Markus
Publicado em 2010

Factors Governing P-Glycoprotein-Mediated Drug–Drug Interactions at the Blood–Brain Barrier Measured with Positron Emission Tomography

Por Wanek, Thomas, Römermann, Kerstin, Mairinger, Severin, Stanek, Johann, Sauberer, Michael, Filip, Thomas, Traxl, Alexander, Kuntner, Claudia, Pahnke, Jens, Bauer, Florian, Erker, Thomas, Löscher, Wolfgang, Müller, Markus, Langer, Oliver
Publicado no Mol Pharm (2015)

Radiosynthesis and in vivo evaluation of 1-[(18)F]fluoroelacridar as a positron emission tomography tracer for P-glycoprotein and breast cancer resistance protein

Por Dörner, Bernd, Kuntner, Claudia, Bankstahl, Jens P., Wanek, Thomas, Bankstahl, Marion, Stanek, Johann, Müllauer, Julia, Bauer, Florian, Mairinger, Severin, Löscher, Wolfgang, Miller, Donald W., Chiba, Peter, Müller, Markus, Erker, Thomas, Langer, Oliver
Publicado em 2011

Efficient Modulation of γ-Aminobutyric Acid Type A Receptors by Piperine Derivatives

Por Schöffmann, Angela, Wimmer, Laurin, Goldmann, Daria, Khom, Sophia, Hintersteiner, Juliane, Baburin, Igor, Schwarz, Thomas, Hintersteininger, Michael, Pakfeifer, Peter, Oufir, Mouhssin, Hamburger, Matthias, Erker, Thomas, Ecker, Gerhard F., Mihovilovic, Marko D., Hering, Steffen
Publicado em 2014

Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity

Por Bollmann, Franziska, Art, Julia, Henke, Jenny, Schrick, Katharina, Besche, Verena, Bros, Matthias, Li, Huige, Siuda, Daniel, Handler, Norbert, Bauer, Florian, Erker, Thomas, Behnke, Felix, Mönch, Bettina, Härdle, Lorena, Hoffmann, Markus, Chen, Ching-Yi, Förstermann, Ulrich, Dirsch, Verena M., Werz, Oliver, Kleinert, Hartmut, Pautz, Andrea
Publicado no Nucleic Acids Res (2014)