A novel PET protocol for visualization of breast cancer resistance protein function at the blood–brain barrier

Breast cancer resistance protein (BCRP) is the most abundant multidrug efflux transporter at the human blood–brain barrier (BBB), restricting brain distribution of various drugs. In this study, we developed a positron emission tomography (PET) protocol to visualize Bcrp function at the murine BBB, b...

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Hlavní autoři: Wanek, Thomas, Kuntner, Claudia, Bankstahl, Jens P, Mairinger, Severin, Bankstahl, Marion, Stanek, Johann, Sauberer, Michael, Filip, Thomas, Erker, Thomas, Müller, Markus, Löscher, Wolfgang, Langer, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493998/
https://ncbi.nlm.nih.gov/pubmed/22828996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.112
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