Chargement en cours...

Factors Governing P-Glycoprotein-Mediated Drug–Drug Interactions at the Blood–Brain Barrier Measured with Positron Emission Tomography

[Image: see text] The adenosine triphosphate-binding cassette transporter P-glycoprotein (ABCB1/Abcb1a) restricts at the blood–brain barrier (BBB) brain distribution of many drugs. ABCB1 may be involved in drug–drug interactions (DDIs) at the BBB, which may lead to changes in brain distribution and...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Pharm
Auteurs principaux: Wanek, Thomas, Römermann, Kerstin, Mairinger, Severin, Stanek, Johann, Sauberer, Michael, Filip, Thomas, Traxl, Alexander, Kuntner, Claudia, Pahnke, Jens, Bauer, Florian, Erker, Thomas, Löscher, Wolfgang, Müller, Markus, Langer, Oliver
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2015
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566129/
https://ncbi.nlm.nih.gov/pubmed/26202880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00168
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!