Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography

Previous data suggest a possible link between multidrug resistance-associated protein 1 (ABCC1) and brain clearance of beta-amyloid (Aβ). We used PET with 6-bromo-7-[(11)C]methylpurine ([(11)C]BMP) to measure cerebral ABCC1 transport activity in a beta-amyloidosis mouse model (APP/PS1-21) and in wil...

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Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Zoufal, Viktoria, Mairinger, Severin, Krohn, Markus, Wanek, Thomas, Filip, Thomas, Sauberer, Michael, Stanek, Johann, Kuntner, Claudia, Pahnke, Jens, Langer, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181082/
https://ncbi.nlm.nih.gov/pubmed/31195936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19854541
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