Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[(11)C]Methylpurine in Mice

PURPOSE: Multidrug resistance-associated proteins (MRPs) mediate the hepatobiliary and renal excretion of many drugs and drug conjugates. The positron emission tomography (PET) tracer 6-bromo-7-[(11)C]methylpurine is rapidly converted in tissues by glutathione-S-transferases into its glutathione con...

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Publicat a:Mol Imaging Biol
Autors principals: Zoufal, Viktoria, Mairinger, Severin, Krohn, Markus, Wanek, Thomas, Filip, Thomas, Sauberer, Michael, Stanek, Johann, Traxl, Alexander, Schuetz, John D., Kuntner, Claudia, Pahnke, Jens, Langer, Oliver
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449286/
https://ncbi.nlm.nih.gov/pubmed/29942989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-018-1230-y
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