Učitavanje...
Imaging P-Glycoprotein Induction at the Blood–Brain Barrier of a β-Amyloidosis Mouse Model with (11)C-Metoclopramide PET
P-glycoprotein (ABC subfamily B member 1, ABCB1) plays an important role at the blood–brain barrier (BBB) in promoting clearance of neurotoxic β-amyloid (Aβ) peptides from the brain into the blood. ABCB1 expression and activity were found to be decreased in the brains of Alzheimer disease patients....
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| Izdano u: | J Nucl Med |
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| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society of Nuclear Medicine
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7383073/ https://ncbi.nlm.nih.gov/pubmed/31806767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.237198 |
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