Imaging P-Glycoprotein Induction at the Blood–Brain Barrier of a β-Amyloidosis Mouse Model with (11)C-Metoclopramide PET

P-glycoprotein (ABC subfamily B member 1, ABCB1) plays an important role at the blood–brain barrier (BBB) in promoting clearance of neurotoxic β-amyloid (Aβ) peptides from the brain into the blood. ABCB1 expression and activity were found to be decreased in the brains of Alzheimer disease patients....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Zoufal, Viktoria, Mairinger, Severin, Brackhan, Mirjam, Krohn, Markus, Filip, Thomas, Sauberer, Michael, Stanek, Johann, Wanek, Thomas, Tournier, Nicolas, Bauer, Martin, Pahnke, Jens, Langer, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2020
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383073/
https://ncbi.nlm.nih.gov/pubmed/31806767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.237198
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados