ERK5 and Cell Proliferation: Nuclear Localization Is What Matters

av Gomez, Nestor, Erazo, Tatiana, Lizcano, Jose M.
I publikationen Front Cell Dev Biol (2016)

SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation

av Erazo, Tatiana, Espinosa-Gil, Sergio, Diéguez-Martínez, Nora, Gómez, Néstor, Lizcano, Jose M
I publikationen Int J Mol Sci (2020)

Canonical and Kinase Activity-Independent Mechanisms for Extracellular Signal-Regulated Kinase 5 (ERK5) Nuclear Translocation Require Dissociation of Hsp90 from the ERK5-Cdc37 Comp...

av Erazo, Tatiana, Moreno, Ana, Ruiz-Babot, Gerard, Rodríguez-Asiain, Arantza, Morrice, Nicholas A., Espadamala, Josep, Bayascas, Jose R., Gómez, Nestor, Lizcano, Jose M.
Publicerad 2013

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

av Elkins, Jonathan M., Wang, Jing, Deng, Xianming, Pattison, Michael J., Arthur, J. Simon C., Erazo, Tatiana, Gomez, Nestor, Lizcano, Jose M., Gray, Nathanael S., Knapp, Stefan
Publicerad 2013

NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death

av Liu, Yuxuan, Mondello, Patrizia, Erazo, Tatiana, Tannan, Neeta Bala, Asgari, Zahra, de Stanchina, Elisa, Nanjangud, Gouri, Seshan, Venkatraman E., Wang, Shenqiu, Wendel, Hans-Guido, Younes, Anas
I publikationen Proc Natl Acad Sci U S A (2018)

BET Inhibition-Induced GSK3β Feedback Enhances Lymphoma Vulnerability to PI3K Inhibitors

av Derenzini, Enrico, Mondello, Patrizia, Erazo, Tatiana, Portelinha, Ana, Liu, Yuxuan, Scallion, Mary, Asgari, Zahra, Philip, John, Hilden, Patrick, Valli, Debora, Rossi, Alessandra, Djaballah, Hakim, Ouerfelli, Ouathek, de Stanchina, Elisa, Seshan, Venkatraman E., Hendrickson, Ronald C., Younes, Anas
I publikationen Cell Rep (2018)

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

av Deng, Xianming, Elkins, Jonathan M., Zhang, Jinwei, Yang, Qingkai, Erazo, Tatiana, Gomez, Nestor, Choi, Hwan Geun, Wang, Jinhua, Dzamko, Nicolas, Lee, Jiing-Dwan, Sim, Taebo, Kim, NamDoo, Alessi, Dario R., Lizcano, Jose M., Knapp, Stefan, Gray, Nathanael S.
Publicerad 2013

The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis

av París-Coderch, Laia, Soriano, Aroa, Jiménez, Carlos, Erazo, Tatiana, Muñoz-Guardiola, Pau, Masanas, Marc, Antonelli, Roberta, Boloix, Ariadna, Alfón, José, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Domènech, Carles, Roma, Josep, Sánchez de Toledo, Josep, Moreno, Lucas, Lizcano, José M., Gallego, Soledad, Segura, Miguel F.
I publikationen Cell Death Dis (2020)

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

av Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Solé, Sònia, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Muñoz-Pinedo, Cristina, Yoldi, Guillermo, Abad, Jose L, Segura, Miguel F, Moran, Teresa, Romeo, Margarita, Bosch-Barrera, Joaquim, Oaknin, Ana, Alfón, Jose, Domènech, Carles, Fabriàs, Gemma, Velasco, Guillermo, Lizcano, Jose M
I publikationen Autophagy (2020)

Structural and atropisomeric factors governing the selectivity of pyrimido-benzodiazipinones as inhibitors of kinases and bromodomains

av Wang, Jinhua, Erazo, Tatiana, Ferguson, Fleur M., Buckley, Dennis L., Gomez, Nestor, Muñoz-Guardiola, Pau, Diéguez-Martínez, Nora, Deng, Xianming, Hao, Mingfeng, Massefski, Walter, Fedorov, Oleg, Offei-Addo, Nana Kwaku, Park, Paul M., Dai, Lingling, DiBona, Amy, Becht, Kelly, Kim, Nam Doo, McKeown, Michael R., Roberts, Justin M., Zhang, Jinwei, Sim, Taebo, Alessi, Dario R., Bradner, James E., Lizcano, Jose M., Blacklow, Stephen C., Qi, Jun, Xu, Xiang, Gray, Nathanael S.
I publikationen ACS Chem Biol (2018)