MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy

Por Segura, Miguel F., Greenwald, Holly S., Hanniford, Doug, Osman, Iman, Hernando, Eva
Publicado em 2012

MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells

Por Yu, Jingyi, Lei, Rong, Zhuang, Xueqian, Li, Xiaoxun, Li, Gang, Lev, Sima, Segura, Miguel F., Zhang, Xue, Hu, Guohong
Publicado no Nat Commun (2016)

TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas

Por Galenkamp, Koen MO, Carriba, Paulina, Urresti, Jorge, Planells-Ferrer, Laura, Coccia, Elena, Lopez-Soriano, Joaquín, Barneda-Zahonero, Bruna, Moubarak, Rana S, Segura, Miguel F, Comella, Joan X
Publicado no Mol Cancer (2015)

Melanoma microRNA signature predicts post-recurrence survival

Por Segura, Miguel F., Belitskaya-Lévy, Ilana, Rose, Amy E., Zakrzewski, Jan, Gaziel, Avital, Hanniford, Douglas, Darvishian, Farbod, Berman, Russell, Shapiro, Richard, Pavlick, Anna, Osman, Iman, Hernando, Eva
Publicado no Clin Cancer Res (2010)

The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma

Por Huynh, Chanh, Poliseno, Laura, Segura, Miguel F., Medicherla, Ratna, Haimovic, Adele, Menendez, Silvia, Shang, Shulian, Pavlick, Anna, Shao, Yongzhao, Darvishian, Farbod, Boylan, John F., Osman, Iman, Hernando, Eva
Publicado em 2011

Correction: The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma

Por Huynh, Chanh, Poliseno, Laura, Segura, Miguel F., Medicherla, Ratna, Haimovic, Adele, Menendez, Silvia, Shang, Shulian, Pavlick, Anna, Shao, Yongzhao, Darvishian, Farbod, Boylan, John F., Osman, Iman, Hernando, Eva
Publicado em 2011

Identification of Metastasis-Suppressive microRNAs in Primary Melanoma

Por Hanniford, Doug, Segura, Miguel F., Zhong, Judy, Philips, Elliot, Jirau-Serrano, Xavier, Darvishian, Farbod, Berman, Russell S., Shapiro, Richard L., Pavlick, Anna C., Brown, Brian, Osman, Iman, Hernando, Eva
Publicado no J Natl Cancer Inst (2015)

Hedgehog Pathway Blockade Inhibits Melanoma Cell Growth in Vitro and in Vivo

Por O’Reilly, Kathryn E., Vega-Saenz de Miera, Eleazar, Segura, Miguel F., Friedman, Erica, Poliseno, Laura, Han, Sung Won, Zhong, Judy, Zavadil, Jiri, Pavlick, Anna, Hernando, Eva, Osman, Iman
Publicado em 2013

The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling

Por Sole, Carme, Dolcet, Xavier, Segura, Miguel F., Gutierrez, Humberto, Diaz-Meco, Maria-Teresa, Gozzelino, Raffaella, Sanchis, Daniel, Bayascas, Jose R., Gallego, Carme, Moscat, Jorge, Davies, Alun M., Comella, Joan X.
Publicado em 2004

Histology-Specific MicroRNA Alterations in Melanoma

Por Poliseno, Laura, Haimovic, Adele, Segura, Miguel F., Hanniford, Douglas, Christos, Paul J., Darvishian, Farbod, Wang, Jinhua, Shapiro, Richard L., Pavlick, Anna C., Berman, Russell S., Hernando, Eva, Zavadil, Jiri, Osman, Iman
Publicado em 2012

Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma

Por Almazán-Moga, Ana, Zarzosa, Patricia, Vidal, Isaac, Molist, Carla, Giralt, Irina, Navarro, Natalia, Soriano, Aroa, Segura, Miguel F., Alfranca, Arantza, Garcia-Castro, Javier, Sánchez de Toledo, José, Roma, Josep, Gallego, Soledad
Publicado no Stem Cells Int (2017)

Dual Pten/Tp53 Suppression Promotes Sarcoma Progression by Activating Notch Signaling

Por Guijarro, Maria V., Dahiya, Sonika, Danielson, Laura S., Segura, Miguel F., Vales-Lara, Frances M., Menendez, Silvia, Popiolek, Dorota, Mittal, Khushbakhat, Wei, Jian Jun, Zavadil, Jiri, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo, Hernando, Eva
Publicado em 2013

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

Por Kapoor, Avnish, Goldberg, Matthew S., Cumberland, Lara K., Ratnakumar, Kajan, Segura, Miguel F., Emanuel, Patrick O., Menendez, Silvia, Vardabasso, Chiara, LeRoy, Gary, Vidal, Claudia I., Polsky, David, Osman, Iman, Garcia, Benjamin A., Hernando, Eva, Bernstein, Emily
Publicado em 2010

BRD4 Sustains Melanoma Proliferation and Represents a New Target for Epigenetic Therapy

Por Segura, Miguel F., Fontanals-Cirera, Bárbara, Gaziel-Sovran, Avital, Guijarro, María V., Hanniford, Doug, Zhang, Guangtao, González-Gomez, Pilar, Morante, Marta, Jubierre, Luz, Zhang, Weijia, Darvishian, Farbod, Ohlmeyer, Michael, Osman, Iman, Zhou, Ming-Ming, Hernando, Eva
Publicado no Cancer Res (2013)

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

Por Segura, Miguel F., Hanniford, Douglas, Menendez, Silvia, Reavie, Linsey, Zou, Xuanyi, Alvarez-Diaz, Silvia, Zakrzewski, Jan, Blochin, Elen, Rose, Amy, Bogunovic, Dusan, Polsky, David, Wei, Jianjun, Lee, Peng, Belitskaya-Levy, Ilana, Bhardwaj, Nina, Osman, Iman, Hernando, Eva
Publicado em 2009

MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes

Por Soriano, Aroa, París-Coderch, Laia, Jubierre, Luz, Martínez, Alba, Zhou, Xiangyu, Piskareva, Olga, Bray, Isabella, Vidal, Isaac, Almazán-Moga, Ana, Molist, Carla, Roma, Josep, Bayascas, José R., Casanovas, Oriol, Stallings, Raymond L., de Toledo, José Sánchez, Gallego, Soledad, Segura, Miguel F.
Publicado no Oncotarget (2016)

MiR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis

Por Gaziel-Sovran, Avital, Segura, Miguel F., Di Micco, Raffaella, Collins, Mary K., Hanniford, Douglas, de Miera, Eleazar Vega-Saenz, Rakus, John F., Dankert, John F., Shang, Shulian, Kerbel, Robert S., Bhardwaj, Nina, Shao, Yongzhao, Darvishian, Farbod, Zavadil, Jiri, Erlebacher, Adrian, Mahal, Lara K., Osman, Iman, Hernando, Eva
Publicado em 2011

Histone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma

Por Vardabasso, Chiara, Gaspar-Maia, Alexandre, Hasson, Dan, Pünzeler, Sebastian, Valle-Garcia, David, Straub, Tobias, Keilhauer, Eva C., Strub, Thomas, Dong, Joanna, Panda, Taniya, Chung, Chi-Yeh, Yao, Jonathan L., Singh, Rajendra, Segura, Miguel F., Fontanals-Cirera, Barbara, Verma, Amit, Mann, Matthias, Hernando, Eva, Hake, Sandra B., Bernstein, Emily
Publicado no Mol Cell (2015)