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TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas

BACKGROUND: Patients with high-risk neuroblastoma (NBL) tumors have a high mortality rate. Consequently, there is an urgent need for the development of new treatments for this condition. Targeting death receptor signaling has been proposed as an alternative to standard chemo- and radio-therapies in...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Galenkamp, Koen MO, Carriba, Paulina, Urresti, Jorge, Planells-Ferrer, Laura, Coccia, Elena, Lopez-Soriano, Joaquín, Barneda-Zahonero, Bruna, Moubarak, Rana S, Segura, Miguel F, Comella, Joan X
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407790/
https://ncbi.nlm.nih.gov/pubmed/25890358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0329-x
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