Amyloid Beta, TNFα and FAIM-L; Approaching New Therapeutic Strategies for AD

Por Carriba, Paulina, Comella, Joan X.
Publicado no Front Neurol (2014)

Neurodegeneration and neuroinflammation: two processes, one target

Por Carriba, Paulina, Comella, Joan X.
Publicado no Neural Regen Res (2015)

Basic Helix-Loop-Helix Proteins Bind to TrkB and p21(Cip1) Promoters Linking Differentiation and Cell Cycle Arrest in Neuroblastoma Cells

Por Liu, Yuhui, Encinas, Mario, Comella, Joan X., Aldea, Martí, Gallego, Carme
Publicado em 2004

Nerve Growth Factor Activation of the Extracellular Signal-Regulated Kinase Pathway Is Modulated by Ca(2+) and Calmodulin

Por Egea, Joaquim, Espinet, Carme, Soler, Rosa M., Peiró, Sandra, Rocamora, Nativitat, Comella, Joan X.
Publicado em 2000

Syntaxin-1/TI-VAMP SNAREs interact with Trk receptors and are required for neurotrophin-dependent outgrowth

Por Fuschini, Giulia, Cotrufo, Tiziana, Ros, Oriol, Muhaisen, Ashraf, Andrés, Rosa, Comella, Joan X., Soriano, Eduardo
Publicado no Oncotarget (2018)

Receptors of the Glial Cell Line-Derived Neurotrophic Factor Family of Neurotrophic Factors Signal Cell Survival through the Phosphatidylinositol 3-Kinase Pathway in Spinal Cord Mo...

Por Soler, Rosa M., Dolcet, Xavier, Encinas, Mario, Egea, Joaquim, Bayascas, Jose R., Comella, Joan X.
Publicado no J Neurosci (1999)

Calmodulin Is Involved in Membrane Depolarization-Mediated Survival of Motoneurons by Phosphatidylinositol-3 Kinase- and MAPK-Independent Pathways

Por Soler, Rosa M., Egea, Joaquim, Mintenig, Gerard M., Sanz-Rodriguez, Cesar, Iglesias, Montse, Comella, Joan X.
Publicado no J Neurosci (1998)

Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons

Por Encinas, Mario, Rozen, Esteban J., Dolcet, Xavier, Jain, Sanjay, Comella, Joan X., Milbrandt, Jeffrey, Johnson, Eugene M.
Publicado em 2008

c-Src Is Required for Glial Cell Line-Derived Neurotrophic Factor (GDNF) Family Ligand-Mediated Neuronal Survival via a Phosphatidylinositol-3 Kinase (PI-3K)-Dependent Pathway

Por Encinas, Mario, Tansey, Malú G., Tsui-Pierchala, Brian A., Comella, Joan X., Milbrandt, Jeffrey, Johnson, Eugene M.
Publicado no J Neurosci (2001)

Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway

Por Fernandez-Gomez, Francisco J, Galindo, Maria F, Gómez-Lázaro, Maria, Yuste, Victor J, Comella, Joan X, Aguirre, Norberto, Jordán, Joaquín
Publicado em 2005

Chromatin Collapse during Caspase-dependent Apoptotic Cell Death Requires DNA Fragmentation Factor, 40-kDa Subunit-/Caspase-activated Deoxyribonuclease-mediated 3′-OH Single-strand...

Por Iglesias-Guimarais, Victoria, Gil-Guiñon, Estel, Sánchez-Osuna, María, Casanelles, Elisenda, García-Belinchón, Mercè, Comella, Joan X., Yuste, Victor J.
Publicado em 2013

Neuronal survival induced by neurotrophins requires calmodulin

Por Egea, Joaquim, Espinet, Carme, Soler, Rosa M., Dolcet, Xavier, Yuste, Víctor J., Encinas, Mario, Iglesias, Montserrat, Rocamora, Nativitat, Comella, Joan X.
Publicado em 2001

Development of Survival Responsiveness to Brain-Derived Neurotrophic Factor, Neurotrophin 3 and Neurotrophin 4/5, But Not to Nerve Growth Factor, in Cultured Motoneurons from Chick...

Por Becker, Elena, Soler, Rosa M., Yuste, Víctor J., Giné, Eva, Sanz-Rodríguez, César, Egea, Joaquim, Martín-Zanca, Dionisio, Comella, Joan X.
Publicado no J Neurosci (1998)

EndoG Links Bnip3-Induced Mitochondrial Damage and Caspase-Independent DNA Fragmentation in Ischemic Cardiomyocytes

Por Zhang, Jisheng, Ye, Junmei, Altafaj, Albert, Cardona, Maria, Bahi, Núria, Llovera, Marta, Cañas, Xavier, Cook, Stuart A., Comella, Joan X., Sanchis, Daniel
Publicado em 2011

Apoptotic DNA Degradation into Oligonucleosomal Fragments, but Not Apoptotic Nuclear Morphology, Relies on a Cytosolic Pool of DFF40/CAD Endonuclease

Por Iglesias-Guimarais, Victoria, Gil-Guiñon, Estel, Gabernet, Gisela, García-Belinchón, Mercè, Sánchez-Osuna, María, Casanelles, Elisenda, Comella, Joan X., Yuste, Victor J.
Publicado em 2012

Oxidative Stress and Proinflammatory Cytokines Contribute to Demyelination and Axonal Damage in a Cerebellar Culture Model of Neuroinflammation

Por di Penta, Alessandra, Moreno, Beatriz, Reix, Stephanie, Fernandez-Diez, Begoña, Villanueva, Maite, Errea, Oihana, Escala, Nagore, Vandenbroeck, Koen, Comella, Joan X., Villoslada, Pablo
Publicado em 2013

X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk

Por Fadó, Rut, Moubarak, Rana S., Miñano-Molina, Alfredo J., Barneda-Zahonero, Bruna, Valero, Jorge, Saura, Carlos A., Moran, Julio, Comella, Joan X., Rodríguez-Álvarez, José
Publicado em 2013

FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration

Por Martínez-Mármol, Ramón, Barneda-Zahonero, Bruna, Soto, David, Andrés, Rosa Maria, Coccia, Elena, Gasull, Xavier, Planells-Ferrer, Laura, Moubarak, Rana S., Soriano, Eduardo, Comella, Joan X.
Publicado no Sci Rep (2016)

TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas

Por Galenkamp, Koen MO, Carriba, Paulina, Urresti, Jorge, Planells-Ferrer, Laura, Coccia, Elena, Lopez-Soriano, Joaquín, Barneda-Zahonero, Bruna, Moubarak, Rana S, Segura, Miguel F, Comella, Joan X
Publicado no Mol Cancer (2015)

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart

Por Ye, Junmei, Llorian, Miriam, Cardona, Maria, Rongvaux, Anthony, Moubarak, Rana S., Comella, Joan X., Bassel-Duby, Rhonda, Flavell, Richard A., Olson, Eric N., Smith, Christopher W. J., Sanchis, Daniel
Publicado em 2013