EndoG Links Bnip3-Induced Mitochondrial Damage and Caspase-Independent DNA Fragmentation in Ischemic Cardiomyocytes

Mitochondrial dysfunction, caspase activation and caspase-dependent DNA fragmentation are involved in cell damage in many tissues. However, differentiated cardiomyocytes repress the expression of the canonical apoptotic pathway and their death during ischemia is caspase-independent. The atypical BH3...

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Main Authors: Zhang, Jisheng, Ye, Junmei, Altafaj, Albert, Cardona, Maria, Bahi, Núria, Llovera, Marta, Cañas, Xavier, Cook, Stuart A., Comella, Joan X., Sanchis, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060094/
https://ncbi.nlm.nih.gov/pubmed/21437288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017998
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