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AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia

The AKT (protein kinase B, PKB) family has been shown to participate in diverse cellular processes, including apoptosis. Previous studies demonstrated that protein kinase B2 (AKT2(−/−)) mice heart was sensitized to apoptosis in response to ischemic injury. However, little is known about the mechanis...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Sci
Main Authors: Yang, Shuai, Zhao, Xinmei, Xu, Hui, Chen, Fan, Xu, Yitao, Li, Zhe, Sanchis, Daniel, Jin, Liang, Zhang, Yubin, Ye, Junmei
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372581/
https://ncbi.nlm.nih.gov/pubmed/28272306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030565
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