Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner

Chemoresistance in cancer has previously been attributed to gene mutations or deficiencies. Bax or p53 deficiency can lead to resistance to cancer drugs. We aimed to find an agent to overcome chemoresistance induced by Bax or p53 deficiency. Here, we used immunoblot, flow-cytometry analysis, gene in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Guo, W, Zhang, Y, Ling, Z, Liu, X, Zhao, X, Yuan, Z, Nie, C, Wei, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632302/
https://ncbi.nlm.nih.gov/pubmed/26469967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.276
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