BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation

Alkylating DNA-damage agents such as N-methyl-N′-nitro-N′-nitrosoguanidine (MNNG) trigger necroptosis, a newly defined form of programmed cell death (PCD) managed by receptor interacting protein kinases. This caspase-independent mode of cell death involves the sequential activation of poly(ADP-ribos...

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Autors principals: Cabon, L, Galán-Malo, P, Bouharrour, A, Delavallée, L, Brunelle-Navas, M-N, Lorenzo, H K, Gross, A, Susin, S A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263500/
https://ncbi.nlm.nih.gov/pubmed/21738214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.91
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