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BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation
Alkylating DNA-damage agents such as N-methyl-N′-nitro-N′-nitrosoguanidine (MNNG) trigger necroptosis, a newly defined form of programmed cell death (PCD) managed by receptor interacting protein kinases. This caspase-independent mode of cell death involves the sequential activation of poly(ADP-ribos...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263500/ https://ncbi.nlm.nih.gov/pubmed/21738214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.91 |
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