Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner

Chemoresistance in cancer has previously been attributed to gene mutations or deficiencies. Bax or p53 deficiency can lead to resistance to cancer drugs. We aimed to find an agent to overcome chemoresistance induced by Bax or p53 deficiency. Here, we used immunoblot, flow-cytometry analysis, gene in...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Guo, W, Zhang, Y, Ling, Z, Liu, X, Zhao, X, Yuan, Z, Nie, C, Wei, Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632302/
https://ncbi.nlm.nih.gov/pubmed/26469967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.276
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