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Bax/Bak activation in the absence of Bid, Bim, Puma, and p53
How BH3-only proteins activate Bax/Bak, the two gateway proteins of the mitochondria-dependent apoptotic pathway, remains incompletely understood. Although all pro-apoptotic BH3-only proteins are known to bind/neutralize the anti-apoptotic Bcl-2 proteins, the three most potent ones, Bid (tBid), Bim,...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5143395/ https://ncbi.nlm.nih.gov/pubmed/27310874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.167 |
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