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BH3 Domains other than Bim and Bid Can Directly Activate Bax/Bak
Bcl-2 family proteins regulate a critical step in apoptosis referred to as mitochondrial outer membrane permeabilization (MOMP). Members of a subgroup of the Bcl-2 family, known as the BH3-only proteins, activate pro-apoptotic effectors (Bax and Bak) to initiate MOMP. They do so by neutralizing pro-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013008/ https://ncbi.nlm.nih.gov/pubmed/21041309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167148 |
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