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Mitochondrial Outer Membrane Proteins Assist Bid in Bax-mediated Lipidic Pore Formation

Mitochondrial outer membrane permeabilization (MOMP) is a critical step in apoptosis and is regulated by Bcl-2 family proteins. In vitro systems using cardiolipin-containing liposomes have demonstrated the key features of MOMP induced by Bax and cleaved Bid; however, the nature of the “pores” and ho...

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Autores principales: Schafer, Blanca, Quispe, Joel, Choudhary, Vineet, Chipuk, Jerry E., Ajero, Teddy G., Du, Han, Schneiter, Roger, Kuwana, Tomomi
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669034/
https://ncbi.nlm.nih.gov/pubmed/19244344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-10-1056
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