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Mitochondrial Outer Membrane Proteins Assist Bid in Bax-mediated Lipidic Pore Formation
Mitochondrial outer membrane permeabilization (MOMP) is a critical step in apoptosis and is regulated by Bcl-2 family proteins. In vitro systems using cardiolipin-containing liposomes have demonstrated the key features of MOMP induced by Bax and cleaved Bid; however, the nature of the “pores” and ho...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669034/ https://ncbi.nlm.nih.gov/pubmed/19244344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-10-1056 |
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