Bax Activation Initiates the Assembly of a Multimeric Catalyst that Facilitates Bax Pore Formation in Mitochondrial Outer Membranes

Bax/Bak-mediated mitochondrial outer membrane permeabilization (MOMP) is essential for “intrinsic” apoptotic cell death. Published studies used synthetic liposomes to reveal an intrinsic pore-forming activity of Bax, but it is unclear how other mitochondrial outer membrane (MOM) proteins might facil...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kushnareva, Yulia, Andreyev, Alexander Y., Kuwana, Tomomi, Newmeyer, Donald D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457932/
https://ncbi.nlm.nih.gov/pubmed/23049480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001394
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