c-Src Is Required for Glial Cell Line-Derived Neurotrophic Factor (GDNF) Family Ligand-Mediated Neuronal Survival via a Phosphatidylinositol-3 Kinase (PI-3K)-Dependent Pathway

The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs), consisting of GDNF, neurturin, persephin, and artemin, signal via a multicomponent complex composed of Ret tyrosine kinase and the glycosyl-phosphatidylinositol (GPI)-anchored coreceptors GFRα1–α4. In previous work we have...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Encinas, Mario, Tansey, Malú G., Tsui-Pierchala, Brian A., Comella, Joan X., Milbrandt, Jeffrey, Johnson, Eugene M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762937/
https://ncbi.nlm.nih.gov/pubmed/11222636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-05-01464.2001
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