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Glial Cell Line-Derived Neurotrophic Factor-Dependent Recruitment of Ret into Lipid Rafts Enhances Signaling by Partitioning Ret from Proteasome-Dependent Degradation

The receptor tyrosine kinase (RTK) Ret is activated by the formation of a complex consisting of ligands such as glial cell line-derived neurotrophic factor (GDNF) and glycerophosphatidylinositol-anchored coreceptors termed GFRαs. During activation, Ret translocates into lipid rafts, which is critica...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pierchala, Brian A., Milbrandt, Jeffrey, Johnson, Eugene M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675173/
https://ncbi.nlm.nih.gov/pubmed/16525057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3420-05.2006
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