Dual Pten/Tp53 Suppression Promotes Sarcoma Progression by Activating Notch Signaling

Soft tissue sarcomas are a heterogeneous group of tumors associated with poor clinical outcome. Although a subset of soft tissue sarcomas is characterized by simple karyotypes and recurrent chromosomal translocations, the mechanisms driving cytogenetically complex sarcomas are largely unknown. Clini...

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Detalhes bibliográficos
Main Authors: Guijarro, Maria V., Dahiya, Sonika, Danielson, Laura S., Segura, Miguel F., Vales-Lara, Frances M., Menendez, Silvia, Popiolek, Dorota, Mittal, Khushbakhat, Wei, Jian Jun, Zavadil, Jiri, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo, Hernando, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668021/
https://ncbi.nlm.nih.gov/pubmed/23708211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.035
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