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NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN
The tumor suppressor PTEN, a critical regulator for multiple cellular processes, is mutated or deleted frequently in various human cancers. Subtle reductions in PTEN expression levels have profound impacts on carcinogenesis. Here we show that PTEN level is regulated by ubiquitin-mediated proteasomal...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828909/ https://ncbi.nlm.nih.gov/pubmed/17218260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.11.039 |
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