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NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN

The tumor suppressor PTEN, a critical regulator for multiple cellular processes, is mutated or deleted frequently in various human cancers. Subtle reductions in PTEN expression levels have profound impacts on carcinogenesis. Here we show that PTEN level is regulated by ubiquitin-mediated proteasomal...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Xinjiang, Trotman, Lloyd, Koppie, Theresa, Alimonti, Andrea, Gao, Zhonghua, Wang, Junru, Erdjument-Bromage, Hediye, Tempst, Paul, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo, Jiang, Xuejun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828909/
https://ncbi.nlm.nih.gov/pubmed/17218260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.11.039
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