ERK5 and Cell Proliferation: Nuclear Localization Is What Matters

di Gomez, Nestor, Erazo, Tatiana, Lizcano, Jose M.
Pubblicato in Front Cell Dev Biol (2016)

SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation

di Erazo, Tatiana, Espinosa-Gil, Sergio, Diéguez-Martínez, Nora, Gómez, Néstor, Lizcano, Jose M
Pubblicato in Int J Mol Sci (2020)

Canonical and Kinase Activity-Independent Mechanisms for Extracellular Signal-Regulated Kinase 5 (ERK5) Nuclear Translocation Require Dissociation of Hsp90 from the ERK5-Cdc37 Comp...

di Erazo, Tatiana, Moreno, Ana, Ruiz-Babot, Gerard, Rodríguez-Asiain, Arantza, Morrice, Nicholas A., Espadamala, Josep, Bayascas, Jose R., Gómez, Nestor, Lizcano, Jose M.
Pubblicazione 2013

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

di Elkins, Jonathan M., Wang, Jing, Deng, Xianming, Pattison, Michael J., Arthur, J. Simon C., Erazo, Tatiana, Gomez, Nestor, Lizcano, Jose M., Gray, Nathanael S., Knapp, Stefan
Pubblicazione 2013

NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death

di Liu, Yuxuan, Mondello, Patrizia, Erazo, Tatiana, Tannan, Neeta Bala, Asgari, Zahra, de Stanchina, Elisa, Nanjangud, Gouri, Seshan, Venkatraman E., Wang, Shenqiu, Wendel, Hans-Guido, Younes, Anas
Pubblicato in Proc Natl Acad Sci U S A (2018)

BET Inhibition-Induced GSK3β Feedback Enhances Lymphoma Vulnerability to PI3K Inhibitors

di Derenzini, Enrico, Mondello, Patrizia, Erazo, Tatiana, Portelinha, Ana, Liu, Yuxuan, Scallion, Mary, Asgari, Zahra, Philip, John, Hilden, Patrick, Valli, Debora, Rossi, Alessandra, Djaballah, Hakim, Ouerfelli, Ouathek, de Stanchina, Elisa, Seshan, Venkatraman E., Hendrickson, Ronald C., Younes, Anas
Pubblicato in Cell Rep (2018)

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

di Deng, Xianming, Elkins, Jonathan M., Zhang, Jinwei, Yang, Qingkai, Erazo, Tatiana, Gomez, Nestor, Choi, Hwan Geun, Wang, Jinhua, Dzamko, Nicolas, Lee, Jiing-Dwan, Sim, Taebo, Kim, NamDoo, Alessi, Dario R., Lizcano, Jose M., Knapp, Stefan, Gray, Nathanael S.
Pubblicazione 2013

The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis

di París-Coderch, Laia, Soriano, Aroa, Jiménez, Carlos, Erazo, Tatiana, Muñoz-Guardiola, Pau, Masanas, Marc, Antonelli, Roberta, Boloix, Ariadna, Alfón, José, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Domènech, Carles, Roma, Josep, Sánchez de Toledo, Josep, Moreno, Lucas, Lizcano, José M., Gallego, Soledad, Segura, Miguel F.
Pubblicato in Cell Death Dis (2020)

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

di Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Solé, Sònia, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Muñoz-Pinedo, Cristina, Yoldi, Guillermo, Abad, Jose L, Segura, Miguel F, Moran, Teresa, Romeo, Margarita, Bosch-Barrera, Joaquim, Oaknin, Ana, Alfón, Jose, Domènech, Carles, Fabriàs, Gemma, Velasco, Guillermo, Lizcano, Jose M
Pubblicato in Autophagy (2020)

Structural and atropisomeric factors governing the selectivity of pyrimido-benzodiazipinones as inhibitors of kinases and bromodomains

di Wang, Jinhua, Erazo, Tatiana, Ferguson, Fleur M., Buckley, Dennis L., Gomez, Nestor, Muñoz-Guardiola, Pau, Diéguez-Martínez, Nora, Deng, Xianming, Hao, Mingfeng, Massefski, Walter, Fedorov, Oleg, Offei-Addo, Nana Kwaku, Park, Paul M., Dai, Lingling, DiBona, Amy, Becht, Kelly, Kim, Nam Doo, McKeown, Michael R., Roberts, Justin M., Zhang, Jinwei, Sim, Taebo, Alessi, Dario R., Bradner, James E., Lizcano, Jose M., Blacklow, Stephen C., Qi, Jun, Xu, Xiang, Gray, Nathanael S.
Pubblicato in ACS Chem Biol (2018)