Molecular Mechanisms and the Role of Saturated Fatty Acids in the Progression of Non-Alcoholic Fatty Liver Disease

Por Leamy, Alexandra K., Egnatchik, Robert A., Young, Jamey D.
Publicado em 2012

Microfluidic mixing for sperm activation and motility analysis of pearl Danio zebrafish

Por Park, Daniel S., Egnatchik, Robert A., Bordelon, Hali, Tiersch, Terrence R., Monroe, W. Todd
Publicado em 2012

Palmitate-induced Activation of Mitochondrial Metabolism Promotes Oxidative Stress and Apoptosis in H4IIEC3 Rat Hepatocytes

Por Egnatchik, Robert A., Leamy, Alexandra K., Noguchi, Yasushi, Shiota, Masakazu, Young, Jamey D.
Publicado em 2013

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload

Por Egnatchik, Robert A., Leamy, Alexandra K., Jacobson, David A., Shiota, Masakazu, Young, Jamey D.
Publicado em 2014

Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells

Por Leamy, Alexandra K., Egnatchik, Robert A., Shiota, Masakazu, Ivanova, Pavlina T., Myers, David S., Brown, H. Alex, Young, Jamey D.
Publicado em 2014

Nanoscale clustering of carbohydrate thiols in mixed SAMs on gold

Por Tantakitti, Faifan, Burk-Rafel, Jesse, Cheng, Fang, Egnatchik, Robert, Owen, Tate, Hoffman, Matt, Weiss, Dirk N., Ratner, Daniel M.
Publicado em 2012

Knockdown of Triglyceride Synthesis Does Not Enhance Palmitate Lipotoxicity or Prevent Oleate-Mediated Rescue in Rat Hepatocytes

Por Leamy, Alexandra K., Hasenour, Clinton M., Egnatchik, Robert A., Trenary, Irina A., Yao, Conghui, Patti, Gary J., Shiota, Masakazu, Young, Jamey D.
Publicado no Biochim Biophys Acta (2016)

LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small cell lung cancer (NSCLC) cells

Por Whang, Young Mi, Park, Serk In, Trenary, Irina A., Egnatchik, Robert A., Fessel, Joshua P., Kaufman, Jacob M., Carbone, David P., Young, Jamey D.
Publicado no Oncogene (2015)

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

Por Griss, Takla, Vincent, Emma E., Egnatchik, Robert, Chen, Jocelyn, Ma, Eric H., Faubert, Brandon, Viollet, Benoit, DeBerardinis, Ralph J., Jones, Russell G.
Publicado no PLoS Biol (2015)

A role for the mitochondrial pyruvate carrier as a repressor of the Warburg Effect and colon cancer cell growth

Por Schell, John C., Olson, Kristofor A., Jiang, Lei, Hawkins, Amy J., Van Vranken, Jonathan G., Xie, Jianxin, Egnatchik, Robert A., Earl, Espen G., Deberardinis, Ralph J., Rutter, Jared
Publicado no Mol Cell (2014)

Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells

Por Rajagopalan, Kartik N., Egnatchik, Robert A., Calvaruso, Maria A., Wasti, Ajla T., Padanad, Mahesh S., Boroughs, Lindsey K., Ko, Bookyung, Hensley, Christopher T., Acar, Melih, Hu, Zeping, Jiang, Lei, Pascual, Juan M., Scaglioni, Pier Paolo, DeBerardinis, Ralph J.
Publicado no Cancer Metab (2015)

Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

Por Jin, Lingtao, Li, Dan, Alesi, Gina N., Fan, Jun, Kang, Hee-Bum, Lu, Zhou, Boggon, Titus J., Jin, Peng, Yi, Hong, Wright, Elizabeth R., Duong, Duc, Seyfried, Nicholas T., Egnatchik, Robert, DeBerardinis, Ralph J., Magliocca, Kelly R., He, Chuan, Arellano, Martha L., Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Kang, Sumin
Publicado no Cancer Cell (2015)