Packing a punch: The mechanism of pore formation by cholesterol dependent cytolysins and Membrane Attack/Perforin-like proteins

Por Dunstone, Michelle A., Tweten, Rodney K.
Publicado em 2012

Cryo-electron tomography: an ideal method to study membrane-associated proteins

Por Dunstone, Michelle A., de Marco, Alex
Publicado no Philos Trans R Soc Lond B Biol Sci (2017)

The mystery behind membrane insertion: a review of the complement membrane attack complex

Por Bayly-Jones, Charles, Bubeck, Doryen, Dunstone, Michelle A.
Publicado no Philos Trans R Soc Lond B Biol Sci (2017)

A New Model for Pore Formation by Cholesterol-Dependent Cytolysins

Por Reboul, Cyril F., Whisstock, James C., Dunstone, Michelle A.
Publicado em 2014

Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer

Por Chia, Jenny, Yeo, Kim Pin, Whisstock, James C., Dunstone, Michelle A., Trapani, Joseph A., Voskoboinik, Ilia
Publicado em 2009

Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within Euteleostomi

Por D’Angelo, Michael E, Dunstone, Michelle A, Whisstock, James C, Trapani, Joseph A, Bird, Phillip I
Publicado em 2012

Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell Determinant

Por Butler, Noah S., Theodossis, Alex, Webb, Andrew I., Nastovska, Roza, Ramarathinam, Sri Harsha, Dunstone, Michelle A., Rossjohn, Jamie, Purcell, Anthony W., Perlman, Stanley
Publicado em 2008

Crystal structure of HLA-G: A nonclassical MHC class I molecule expressed at the fetal–maternal interface

Por Clements, Craig S., Kjer-Nielsen, Lars, Kostenko, Lyudmila, Hoare, Hilary L., Dunstone, Michelle A., Moses, Eric, Freed, Katy, Brooks, Andrew G., Rossjohn, Jamie, McCluskey, James
Publicado em 2005

Screening of 71 P. multocida Proteins for Protective Efficacy in a Fowl Cholera Infection Model and Characterization of the Protective Antigen PlpE

Por Hatfaludi, Tamás, Al-Hasani, Keith, Gong, Lan, Boyce, John D., Ford, Mark, Wilkie, Ian W., Quinsey, Noelene, Dunstone, Michelle A., Hoke, David E., Adler, Ben
Publicado em 2012

The Perforin Pore Facilitates the Delivery of Cationic Cargos

Por Stewart, Sarah E., Kondos, Stephanie C., Matthews, Antony Y., D'Angelo, Michael E., Dunstone, Michelle A., Whisstock, James C., Trapani, Joseph A., Bird, Phillip I.
Publicado em 2014

Epitope-specific TCRβ repertoire diversity imparts no functional advantage on the CD8(+) T cell response to cognate viral peptides

Por La Gruta, Nicole L., Thomas, Paul G., Webb, Andrew I., Dunstone, Michelle A., Cukalac, Tania, Doherty, Peter C., Purcell, Anthony W., Rossjohn, Jamie, Turner, Stephen J.
Publicado em 2008

Crystal structure of the human T cell receptor CD3εγ heterodimer complexed to the therapeutic mAb OKT3

Por Kjer-Nielsen, Lars, Dunstone, Michelle A., Kostenko, Lyudmila, Ely, Lauren K., Beddoe, Travis, Mifsud, Nicole A., Purcell, Anthony W., Brooks, Andrew G., McCluskey, James, Rossjohn, Jamie
Publicado em 2004

The MACPF/CDC family of pore-forming toxins

Por Rosado, Carlos J, Kondos, Stephanie, Bull, Tara E, Kuiper, Michael J, Law, Ruby H P, Buckle, Ashley M, Voskoboinik, Ilia, Bird, Phillip I, Trapani, Joseph A, Whisstock, James C, Dunstone, Michelle A
Publicado em 2008

The Cellular Redox Environment Alters Antigen Presentation

Por Trujillo, Jonathan A., Croft, Nathan P., Dudek, Nadine L., Channappanavar, Rudragouda, Theodossis, Alex, Webb, Andrew I., Dunstone, Michelle A., Illing, Patricia T., Butler, Noah S., Fett, Craig, Tscharke, David C., Rossjohn, Jamie, Perlman, Stanley, Purcell, Anthony W.
Publicado em 2014

Enzymatic Properties of an Ecto-nucleoside Triphosphate Diphosphohydrolase from Legionella pneumophila: SUBSTRATE SPECIFICITY AND REQUIREMENT FOR VIRULENCE

Por Sansom, Fiona M., Riedmaier, Patrice, Newton, Hayley J., Dunstone, Michelle A., Müller, Christa E., Stephan, Holger, Byres, Emma, Beddoe, Travis, Rossjohn, Jamie, Cowan, Peter J., d'Apice, Anthony J. F., Robson, Simon C., Hartland, Elizabeth L.
Publicado em 2008

Stonefish toxin defines an ancient branch of the perforin-like superfamily

Por Ellisdon, Andrew M., Reboul, Cyril F., Panjikar, Santosh, Huynh, Kitmun, Oellig, Christine A., Winter, Kelly L., Dunstone, Michelle A., Hodgson, Wayne C., Seymour, Jamie, Dearden, Peter K., Tweten, Rodney K., Whisstock, James C., McGowan, Sheena
Publicado no Proc Natl Acad Sci U S A (2015)

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Por Theodossis, Alex, Guillonneau, Carole, Welland, Andrew, Ely, Lauren K., Clements, Craig S., Williamson, Nicholas A., Webb, Andrew I., Wilce, Jacqueline A., Mulder, Roger J., Dunstone, Michelle A., Doherty, Peter C., McCluskey, James, Purcell, Anthony W., Turner, Stephen J., Rossjohn, Jamie
Publicado em 2010

Correction: Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

Por Leung, Carl, Dudkina, Natalya V, Lukoyanova, Natalya, Hodel, Adrian W, Farabella, Irene, Pandurangan, Arun P, Jahan, Nasrin, Damaso, Mafalda Pires, Osmanović, Dino, Reboul, Cyril F, Dunstone, Michelle A, Andrew, Peter W, Lonnen, Rana, Topf, Maya, Saibil, Helen R, Hoogenboom, Bart W
Publicado no eLife (2015)

Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

Por Leung, Carl, Dudkina, Natalya V, Lukoyanova, Natalya, Hodel, Adrian W, Farabella, Irene, Pandurangan, Arun P, Jahan, Nasrin, Pires Damaso, Mafalda, Osmanović, Dino, Reboul, Cyril F, Dunstone, Michelle A, Andrew, Peter W, Lonnen, Rana, Topf, Maya, Saibil, Helen R, Hoogenboom, Bart W
Publicado no eLife (2014)

Structure of the poly-C9 component of the complement membrane attack complex

Por Dudkina, Natalya V., Spicer, Bradley A., Reboul, Cyril F., Conroy, Paul J., Lukoyanova, Natalya, Elmlund, Hans, Law, Ruby H. P., Ekkel, Susan M., Kondos, Stephanie C., Goode, Robert J. A., Ramm, Georg, Whisstock, James C., Saibil, Helen R., Dunstone, Michelle A.
Publicado no Nat Commun (2016)