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The mystery behind membrane insertion: a review of the complement membrane attack complex

The membrane attack complex (MAC) is an important innate immune effector of the complement terminal pathway that forms cytotoxic pores on the surface of microbes. Despite many years of research, MAC structure and mechanism of action have remained elusive, relying heavily on modelling and inference f...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: Bayly-Jones, Charles, Bubeck, Doryen, Dunstone, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483522/
https://ncbi.nlm.nih.gov/pubmed/28630159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0221
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